Immediately from the ACCP Pulmonary drugs Board evaluation 2009 path, this article covers each subject in a concise, easy-to-use layout. Use as a self-study source to organize for the pulmonary drugs subspecialty board exam.
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Extra resources for ACCP Pulmonary Medicine Board Review: 25th Edition
Clinical review: CF. BMJ 2007; 335:125551–125259 This article includes up-to-date tables with informal evidence grading of management strategies in CF. Davis PB. Centennial review: CF since 1938. Am J Respir Crit Care Med 2006; 173:475–482 This article summarizes the history of CF since it was distinguished from celiac disease in 1938. The standardization of the sweat test in 1959 allowed the identification of milder cases. In 1983, chloride transport was identified as the basic CF defect. In 1989, the CF gene was discovered.
Interventional catheter extraction or fragmentation may become viable options for these patients in the near future. These are patients undergoing hip or knee arthroplasty, hip fracture surgery, or patients who have had major trauma or spinal cord injury. The recommended prophylaxis is LMWH, fondaparinux, or an oral vitamin K antagonist (international normalized ratio 2 to 3). As in moderate-risk patients, if the bleeding risk is extremely high, mechanical methods of prophylaxis should be used.
Treatment of PAH No treatment for PAH has been found to achieve a cure for this devastating disease. There are six main types of treatment for PAH. The first is prevention. Because some forms of PAH have clear causal mechanisms, these factors should be eliminated where possible. The second line of treatment is screening of high-risk patients (as previously discussed) because it is generally believed that earlier diagnosis and treatment may improve outcomes. The third is to optimize the therapy for any related diseases, such as heart failure, hypoxemia, sleep disorders, or collagen vascular diseases.
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